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Structural mitochondrial abnormalities have been seen in muscle biopsies from ME/CFS patients (382), but this is not observed in other studies (383)
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Vitamin B12 (cobalamin) is an essential water-soluble vitamin that plays a crucial role in red blood cell formation, neurological function, and DNA synthesis
This vitamin b12 deficiency skin problems tend to cause darkening of the skin, patchy, especially on the hands, feet, and joints
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